This article first appeared on GuruFocus.

Personalis Inc (NASDAQ:PSNL) is set to release its Q3 2025 earnings on Nov 4, 2025. The consensus estimate for Q3 2025 revenue is $13.31 million, and the earnings are expected to come in at -$0.28 per share. The full year 2025's revenue is expected to be $73.15 million and the earnings are expected to be -$0.96 per share. More detailed estimate data can be found on the Forecast page.

Warning! GuruFocus has detected 6 Warning Signs with PSNL.

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Over the past 90 days, revenue estimates for Personalis Inc (NASDAQ:PSNL) have declined from $83.33 million to $73.15 million for the full year 2025, and from $104.78 million to $94.97 million for 2026. Earnings estimates have declined from -$0.94 per share to -$0.96 per share for the full year 2025, while they have increased from -$0.92 per share to -$0.91 per share for 2026.

In the previous quarter ending June 30, 2025, Personalis Inc's (NASDAQ:PSNL) actual revenue was $17.20 million, which missed analysts' revenue expectations of $20.11 million by -14.47%. Personalis Inc's (NASDAQ:PSNL) actual earnings were -$0.23 per share, which beat analysts' earnings expectations of -$0.24 per share by 5.74%. After releasing the results, Personalis Inc (NASDAQ:PSNL) was down by -21.90% in one day.

Based on the one-year price targets offered by 8 analysts, the average target price for Personalis Inc (NASDAQ:PSNL) is $7.44, with a high estimate of $11.00 and a low estimate of $5.00. The average target implies a downside of -22.69% from the current price of $9.62.

Based on GuruFocus estimates, the estimated GF Value for Personalis Inc (NASDAQ:PSNL) in one year is $1.79, suggesting a downside of -81.39% from the current price of $9.62.

Based on the consensus recommendation from 8 brokerage firms, Personalis Inc's (NASDAQ:PSNL) average brokerage recommendation is currently 1.9, indicating an \\"Outperform\\" status. The rating scale ranges from 1 to 5, where 1 signifies strong buy, and 5 denotes sell.